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HUMAN Tissue

iSpecimen procures a range of solid tissue samples from healthy patients and those with medical conditions such as all types of cancers and benign conditions. Because we have access to the full electronic medical record, we can select and annotate specimens with molecular and genetic characterizations, treatment data, outcomes data, and other pertinent patient and specimen data. Human tissue is also available in matched sets of tumor tissue, normal adjacent tissue, biofluids, and/or cells as well as longitudinal collections from the same patient. Solid tissue formats we offer include:

 

  • Fresh, frozen, or fixed tissue
  • Formalin-fixed paraffin-embedded (FFPE) blocks
  • Stained or unstained slides
  • Whole tissue
  • Tissue microarrays (TMA)
Solid Tissue

high quality tissue specimens

The iSpecimen Marketplace is your one-stop source for all types of human samples. We offer matched sets of solid tissue, in addition to biofluids and viable cells, and can procure both research-use and remnant samples, either banked or prospectively-collected. We also provide post-mortem samples for those who need whole organs or other material not typically collected from live donors.

A New Commercial Market

recent tissue projects and collections

BANKED FFPE

  • NSCLC blocks or unstained slides: 500+ cases including resections and core needle biopsies.

Primary and metastatic lesions, EGFR status needed, >20% tumor content.

  • Colorectal Ca MSI-H: 50 cases of CRC including 12-25 cases MSI-H. Tumor blocks with matched normal adjacent tissue.
  • Kidney FFPE blocks: 20 cases – 10 from patients with diabetic nephropathy and 10 from

patients with hypertensive nephropathy. Pathologic diagnosis and disease stage required.

  • Solid tumor type with approved immuno-therapy blocks or unstained slides: 6 cancer types –

60 samples each (total 360 cases): NSCLC, bladder, kidney, head & neck, melanoma, TNBC.

Samples from naïve and post-IO. Matched, frozen PBMCs a plus.

 

PROSPECTIVELY COLLECTED FRESH TISSUE

  • Ovarian Ca – fresh tissue and peritoneal fluid: 30+ cases with ≥200mg tissue (ischemic time

<60 min) with peritoneal fluid (500-1000cc).

  • Multiple tumor sites – fresh tissue: 10 each from carcinoma of breast, lung, kidney, GI, and

ovarian as well as melanoma. 100-200mg each, <60 min ischemic time.

  • Invasive Breast Ca, HER2+ preferred, advanced stage – fresh tissue and blood. 15 samples

with matching blood. Cores (3-4) or resection (3mm punch), LN mets acceptable.

  • Lung AdenoCa, advanced stage, untreated – fresh tissue: 30 cases distributed between

combinations of smokers and non-smokers, male and female, Asian and Caucasian.

 

BANKED FROZEN TISSUE

  • Normal Tissue – frozen normal tissue from CNS, liver, adrenal, kidney, GI, bladder: 500+ cases. Large volumes per sample, if possible. Collection date 2013 or after.
  • Pancreatic Ca – frozen tissue: 9 cases with tumor >50%, 1gm tissue each. Copy of redacted

path report.

  • Soft Tissue Tumors of various types, Stage II or III – frozen tissue 500+ cases, >30% tumor.

Large volumes per sample. Recent collection date.

 

Custom Study Design

biospecimen collection and custom Study Design

We work with iSpecimen Partner sites to collect, process, and ship human tissue specimens. Most specimens are shipped to iSpecimen and go through our QA process before being sent to researchers. We also offer additional processing services, such as DNA extraction.

When you require a custom collection of solid tissue samples, iSpecimen Concierges are here to help. They can also help with study design, site selection, and compliance management, in addition to specimen collection, processing, and shipping.

The iSpecimen Marketplace

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