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Category: Advancements in Research

HIV remission cases fuel hope for cure

March 14, 2019

Although the AIDS epidemic has ebbed, HIV infection remains prevalent, with about 5,000 new infections per day and nearly 37 million living with the virus. Thus, news this week that a second and third HIV infected patient appear to have recently been “cured” of the infection has kindled hope in the medical and patient communities.

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Microscope lenses

Promising Alzheimer’s research spotlights cellular cleaning system

February 28, 2019

Like household clutter hiding a homeowner’s keys, a malfunctioning cleaning system in brain cells is being linked to Alzheimer’s disease, according to new research. Improving the cellular cleaning system in lab animals makes Alzheimer’s symptoms nearly disappear, researchers say. Researchers have discovered that humans and animals with Alzheimer’s show signs of compromised mitophagy, the process […]

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hands holding a grocery hand basket filled with vegetables

Scientists uncover more gut-brain connections

February 14, 2019

They’re foreign to us, yet part of us. Do the trillions of microbes in and on our bodies control us? Well, these bacteria, fungi, protozoa and viruses – collectively called the microbiome – are quite likely affecting our brains and behavior to some degree.

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Woman smiling

Gene-based treatments show promise against sickle cell disease

February 7, 2019

Sickle cell disease, a group of blood disorders affecting more than 70,000 Americans, including about 1 in 500 African-Americans, is the target of new gene-related therapies that are delivering impressive results.

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Brain cancer differs markedly between men and women

February 1, 2019

The malignant brain cancer glioblastoma behaves distinctly differently in men and women, according to new research. The newly discovered insights may elevate sex as an important factor in how patients are treated.

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Diabetes monitor

The gut can affect how your diabetes medicine works – or doesn’t

January 17, 2019

In simple terms, you can think of medicine as a contest between disease and drugs. New research, however, spotlights an interloper in that relationship: the gut. The trillions of microbial cells in our gut – the human microbiome– can affect digestion, immunity and mood. They may also help determine why certain drugs work for some individuals but not for others, and why drugs sometimes work when delivered intravenously but not orally (or the other way around).

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Tree in the forest

For better heart health, seek out trees

January 10, 2019

Although humans increasingly dwell in concrete, car-clogged cities and spend most of their time indoors, the natural world offers tangible health benefits we probably can’t afford to miss. The latest finding: Leafy green neighborhoods may lower the risk of heart disease and strokes, according to new research published in the Journal of the American Heart Association. Human biospecimens tell the story.

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big data and human biobanks create genetic insights

Big data keeps genomic insights coming

January 3, 2019

Combining big data about people and their genes yields surprising insights, including new clues that help explain individual differences in activity levels (as well as the consequences of those differences), and the origin of red hair. In the activity-level research, University of Oxford scientists identified 14 genetic regions related to activity and sleep duration, seven […]

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First-of-its-kind test might detect all cancer types

December 13, 2018

Imagine one simple, noninvasive test capable of detecting the presence of cancer, regardless of its type or location in the patient’s body, in just 10 minutes. That’s the possibility raised by an attention-grabbing discovery revealed last week based on research in Australia. Researchers from the University of Queensland discovered that traces of human DNA from […]

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Biospecimen Cells for Obesity Research

Researchers probe obesity’s complex roots

December 6, 2018

How do genes affect obesity? And how do environmental factors affect obesity-relevant genes? These are unsettled questions, but researchers like epidemiology professor Kari North, Ph.D., are working on answers. Last year, North and a colleague led research that found that smoking may increase genetic susceptibility to being generally overweight and reduces genetic effects on body fat distribution […]

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